There has been rampant speculation that Steelers' great Franco Harris will run against Senator Arlen Specter in 2010. The last time a jock ran statewide he got clobbered. I think the difference is that Lynn Swann went from being a sideline reporter to candidate without paying his political dues. That and he had the the misfortune of running against a popular incumbent Governor. Harris appears on the football pregame shows but he has also been involved in Democratic party politics.
Harris was an Obama delegate at the Democratic National Convention and a campaign surrogate and I think that it would be a good bet that the President would campaign for him. He also helped raise money for Democratic candidates even attending a fundraiser in Williamsport for one of my favorite Congresscritters, Chris Carney, in his longshot campaign in 2006. BTW, Carney won with just a little help from Franco.